HUMAN REPRODUCTION

 

Oogenesis:

  • Formation of a mature female gamete or ovum is called oogenesis.
  • Oogenesis starts during embryonic stage, 25th week of the fetal age.
  • Germinal epithelium of ovary divided mitotically to produce millions of gamete mother cell or oogonia.
  • No oogonia formed or added after birth.
  • Oogonia enters into meiosis-I and proceeds upto diakinesis of Prophase-I and get suspended, at this stage called primary Oocytes.
  • Each primary oocyte surrounded by layers of granulose cells and then called primary follicle.
  • At puberty only 60,000 to 80,000 primary oocytes are left in each ovary.
  • After puberty primary follicles get surrounded by more layers of granulosa cells and a new theca to form secondary follicles.
  • The secondary follicle transformed into tertiary follicle, characterized by a fluid filled cavity called antrum.
  • The theca layers organized into an inner theca interna and outer theca externa.
  • During the growth of primary follicle into tertiary follicle during puberty, the primary oocyte restarts its first meiotic division and completes it within tertiary follicle resulting two unequal haploid cells.
    • Large haploid cell is called secondary oocyte.
    • A tiny cell called first polar body.
  • The secondary oocyte retains bulk of the nutrient rich cytoplasm of primary oocyte.
  • The tertiary follicle having secondary oocyte further changes into Graafian follicle.
  • The secondary oocyte surrounded by a new membrane, zona pellucida.
  • The secondary oocyte undergoes second meiotic division continued upto metaphase-II and get suspended until entry of sperm.
  • At this stage Graafian follicle releases secondary oocyte from the ovary by the process called ovulation.
  • On entry of a sperm into the secondary oocytes stimulates it to complete meiosis-II and there is formation of a haploid ovum and a second polar body (n).

Menstrual cycle:

  • Reproductive cycle of female primates is called menstrual cycle.
  • The first menstruation begins at puberty is called Menarche.
  • Menstrual cycle repeated at an average interval of 28/29 days.
  • One ovum is released in the middle of each menstrual cycle.

Menstrual  cycle has following phases:

Menstrual phase:

  • 1st phase of menstrual cycle.
  • Menstrual flow occurs.
  • Lasts for 3-5 days.
  • Breakdown of endometrial lining and blood vessel.
  • Mucus and blood comes out through vagina.
  • It occurs only when ovum released but no fertilization.
  • Lack of menstruation is the indication of pregnancy.

Follicular phase:

  • Menstrual phase followed by follicular phase.
  • Primary follicle becomes Graafian follicle.
  • Regeneration and proliferation of uterine endometrium.
  • LH and FSH level increases gradually in follicular phase.
  • Level of estrogen increases as it is secreted from growing follicle.
  • It lasts for 5-13 days.

Ovulatory phase:

  • FSH and LH attain peak level in this period (14th day).
  • This is called LH surge, which induces rupture of Graafian follicle and release of ovum from the ovary called ovulation.

Luteal phase:

  • Remaining part of Graafian follicle transformed into corpus luteum.
  • Coupus luteum produces large amount of progesterone.
  • Progesterone maintains the uterine endometrium, and prepares it for implantation.
  • Thickness of uterine endometrium increase in many folds, due to proliferation.
  • If there is fertilization, corpus luteum grows further and pregnancy continued, menstrual cycle stopped.
  • In the absence of fertilization corpus luteum degenerates.
  • Disintegration of endometrium leading to menstruation.
  • Menstrual cycle ceases around 50 years of age, called menopause.

 

CBSE Biology (Chapter Wise) Class XII ( By Mr. Hare Krushna Giri )
Email Id : harekrushnagiri@yahoo.com



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